منابع مشابه
Allatostatin-C receptors in mosquitoes.
In the present work we describe the functional and molecular characterization of two Aedes aegypti allatostatin-C receptor paralogs (AeAS-CrA and AeAS-CrB) and provide a detailed quantitative study of the expression of the AS-C receptor genes in an adult insect. The tissue distribution of the two AS-C receptors differed significantly; the mRNA levels of AeAS-CrB in the Malpighian tubules were t...
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C. elegans has numerous putative cell adhesion receptors, many of which have vertebrate homologues. The simple body plan of C. elegans, its optical transparency and genetic tractability make it well suited for the study of adhesion receptors and their associated complexes (reviewed by Cox and Hardin in this issue, pp. 1885-1897). We focus here on receptors that are likely to directly mediate ad...
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Nuclear receptors (NRs) are transcription factors typically regulated by lipophilic hormones, which coordinate metazoan metabolism, development and homeostasis. C. elegans has undergone a remarkable expansion of the family, harboring 284 of these receptors in its genome. Approximately 20 of them have been analyzed genetically, most of which correspond to conserved homologs in other metazoans. T...
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The neuropeptide allatostatin-A (AstA) and its cognate receptors (AstARs) are involved in the modulation of feeding behavior, which in hematophagous insects includes the regulation of the disease vector-related behaviors, host seeking and blood feeding. In mosquitoes and other dipterans, there are two copies of AstAR, contrasting with the single copy found in other insects. In this study, we id...
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Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115 neuropeptide genes, testing whether they affected growth. NLP-24 peptides have a conserved YGGXX sequence, similar to mammalian opioid neurope...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2010
ISSN: 1664-2392
DOI: 10.3389/conf.fendo.2010.01.00019